Polynucleotides

WHAT IS IT?

Polynucleotides work by supporting the skin’s natural repair processes at a cellular level. When introduced through superficial injections, these molecules serve as catalysts for tissue repair, prompting fibroblasts to produce more collagen and thereby enhancing the overall structure of the skin.

Rather than simply adding moisture or volume, polynucleotides stimulate the skin’s inherent ability to heal itself, which can lead to a complexion that looks more youthful and naturally refreshed.

During treatment, these compounds are carefully infused into the targeted areas, where they integrate with the skin’s cells. Over time, the activation of the skin’s repair mechanisms helps improve texture and elasticity, while also evening out tone and reducing the appearance of fine lines. The overall effect is often described as a subtle yet noticeable enhancement in skin quality, where the natural glow and firmness are restored from within.

A series of sessions is generally recommended to achieve optimal outcomes, with yearly maintenance treatments to help sustain the benefits over time.

Looking ahead, there is an exciting possibility of integrating advanced regenerative elements that build on this principle. While the specifics of these future approaches are still being explored, they hint at a more sophisticated direction in aesthetic treatments, potentially offering even more refined ways to enhance skin health without relying solely on traditional methods.

Polynucleotides work differently from skin boosters, offering deeper regenerative benefits by stimulating cellular repair and tissue regeneration. They provide long-term improvements in skin health and function, making them an excellent choice for clients looking for natural, science-backed skin rejuvenation. Here’s how they target different concerns:

Fine Lines and Wrinkles: Rather than just hydrating the skin like skin boosters, polynucleotides actively stimulate fibroblasts, promoting collagen and elastin production. This results in the gradual softening of fine lines and wrinkles while improving overall skin structure
Dull or Dehydrated Skin: Polynucleotides don’t just provide hydration; they enhance the skin’s ability to retain moisture by improving cellular function. This leads to long-lasting improvements in skin radiance, making it ideal for tired, stressed, or environmentally damaged skin.
Elasticity and Firmness: As polynucleotides stimulate tissue repair, they significantly improve skin elasticity and firmness. They are particularly effective for areas prone to laxity, such as the under-eye area, neck, and hands, where skin boosters might not offer the same regenerative potential.
Texture and Pore Size: By improving overall skin quality at a cellular level, polynucleotides refine skin texture, reduce roughness, and help tighten pores over time. Their ability to support dermal restructuring makes them a superior choice for skin renewal.
Acne Scarring and Uneven Skin Tone: Polynucleotides are known for their wound-healing properties, making them highly effective for improving acne scars, post-inflammatory hyperpigmentation, and overall skin tone irregularities. Unlike skin boosters, which primarily hydrate, polynucleotides actively remodel tissue, leading to visible improvements in scarring.

Unsuitable Candidates

Certain individuals may not be appropriate candidates for polynucleotide treatments. If you fall into any of the following categories, it is advisable to consult with your practitioner to discuss alternative options:

Active Skin Conditions: Individuals with active infections, rashes, or irritations in the treatment area should postpone their procedure until the condition is resolved.
Severe Allergies: Those with a history of severe allergic reactions to fish or any components of the polynucleotide formulation should avoid this treatment.
Autoimmune Diseases: Individuals with autoimmune disorders may have altered healing responses, making them less suitable for this treatment.
Blood Disorders: Conditions affecting blood clotting or individuals on blood-thinning medications may be at increased risk of bruising or bleeding during the treatment.
Pregnancy and Breastfeeding: Elective cosmetic procedures are generally avoided during pregnancy and breastfeeding due to potential risks and limited research.
Recent Cosmetic Procedures: Individuals who have undergone other aesthetic treatments, such as chemical peels or laser treatments, should wait for the recommended recovery period before getting polynucleotides.

Conditional Candidates

Some individuals may still be eligible for polynucleotide treatments but require careful assessment and discussion with their practitioner to establish a tailored and safe treatment plan. These conditional candidates include:

Individuals on Blood Thinners: Those taking blood-thinning medications may need to adjust their regimen around the time of treatment under medical supervision to reduce the risk of bleeding and bruising.
History of Cold Sores: Individuals with a history of cold sores may need to take antiviral medication before and after the procedure to prevent outbreaks. This is mostly for when targeting the lip area.
Recent Cosmetic Treatments: Patients who have recently had other cosmetic procedures may need to wait a specific time frame to ensure proper healing and avoid complications.
Sensitive Skin: Those with sensitive skin may require additional consideration regarding the products used and the technique applied to minimise any potential adverse reactions.
Hormonal Changes: Individuals experiencing hormonal fluctuations (e.g., during menstruation or hormonal treatments) may experience increased sensitivity and should communicate this to their practitioner.

Before proceeding with polynucleotides it’s essential to have a consultation to evaluate individual circumstances and ensure a safe and effective treatment plan tailored to your needs.

Potential Side Effects

All cosmetic procedures carry risks. Understanding potential side effects allows for informed decisions. Despite personalised treatments and aftercare, complications may occur. Knowing these risks helps you address concerns with your practitioner and prioritise safety.

Common Side Effects

When undergoing polynucleotide treatments, some side effects may occur, although they are typically mild and temporary. Common side effects include:

Swelling: Mild to moderate swelling at the injection site is common and usually subsides within a few hours to a couple of days.
Bruising: Small bruises may develop where the injections were made. This can be managed with ice and typically resolves within a week.
Redness: Temporary redness around the injection sites is normal and generally fades shortly after the procedure.
Tenderness: Some individuals may experience tenderness or sensitivity in the treated areas, which usually resolves within a few days.
Lumps or Bumps Under the Skin: After a polynucleotide injection, you may notice more prominent, fluid-filled bumps at the injection site compared to skin boosters. These temporary lumps form as the product integrates into the tissue and are a normal response to the injection process. Typically, they begin to subside within 24 to 48 hours as the substance is gradually absorbed.

Less Common Side Effects

While less common, certain side effects may occur and should be monitored:

Infection: Although rare, there is a risk of infection at the injection sites. Proper hygiene and aftercare can help minimise this risk.
Allergic Reactions: Some individuals may experience allergic reactions to the components of the polynucleotide. This could manifest as rash, itching, or swelling.

If you experience any side effects following a skin booster treatment that cause concern or persist beyond the expected timeframe, it's essential to contact your practitioner for further guidance.

Precare

Medication: If possible, discontinue any medications that may increase your risk of bleeding, such as aspirin, fish oil, or ibuprofen, at least 7 days prior to your appointment. However, do not stop any medication if it's medically necessary; please discuss with your practitioner for tailored advice.
Active Skincare Products: Avoid using active skincare products, including retinol and AHA/BHA, for at least 3 days before the procedure to minimise skin sensitivity.
Exercise and Alcohol: Refrain from heavy exercise and alcohol consumption for 24 hours before your appointment to help reduce the risk of bruising and swelling.
Makeup-Free Arrival: Please arrive without makeup to ensure a clean treatment area.
Pain Management: Take paracetamol and a non-drowsy antihistamine about 1 hour prior to your appointment to minimise discomfort

Aftercare

Touching the Area: Avoid touching the treated area for at least 6 hours, ideally 12 hours, to reduce the risk of infection. Anything touching the face should be clean e.g. hands, pillowcase, towels.
Alcohol Consumption: Steer clear of heavy alcohol consumption for 24 hours after the treatment to minimise bruising.
Makeup: Refrain from applying makeup on the treated area for approximately 24 hours.
Exercise: Avoid heavy exercise for 24 hours post-treatment to limit swelling.
Active Skincare Products: Hold off on using active skincare products, such as retinol and AHA/BHA, for 3 days after the procedure.
Skin Treatments: Avoid facials, sunbeds, chemical peels for 14 days post-treatment to ensure proper healing.
UV and Extreme Heat Exposure: Stay away from UV exposure and extreme heat, such as saunas and steam rooms, for 2 weeks, as this can increase discomfort and swelling.
Cold Compresses: Avoid applying extreme cold directly to the skin, but if necessary, you can use a clean cool compress to alleviate discomfort or swelling.
Bruising Management: Consider using arnica tablets or gel to help reduce bruising.

By following these specific pre-care and post-care instructions, you can optimise your polynucleotide treatment experience and ensure the best possible results.

How long until I see results?

Polynucleotides work by stimulating natural skin regeneration, so results develop gradually over time. Many clients notice improved skin texture and hydration within a few weeks, with more visible firmness, elasticity, and radiance after 4 to 6 weeks. For optimal results, a course of 3 to 4 treatments is usually recommended, spaced 2 to 4 weeks apart.

Are polynucleotides made from salmon sperm?

Polynucleotides are derived from purified fish DNA, typically sourced from salmon or trout. The DNA is extracted from fish sperm or gonads, but it undergoes a rigorous purification process to remove proteins and immunogenic components, leaving only the beneficial polynucleotide chains. This ensures the product is safe, highly biocompatible, and effective for skin regeneration. While polynucleotides are not allergenic like traditional fish-based products, individuals with severe fish allergies should take more care and consult their practitioner before treatment.

How long do the results of polynucleotides last?

The results of polynucleotide treatments can last up to a year after completing a course of 3 to 4 sessions, typically spaced 2 to 4 weeks apart. Since polynucleotides stimulate long-term skin regeneration, the benefits continue to develop over time. However, to maintain and enhance results, maintenance sessions are usually recommended every 6 to 12 months, depending on individual skin needs and lifestyle factors.

Is the procedure painful?

Most clients report minimal discomfort during the procedure. A topical anaesthetic is applied beforehand to numb the area, and the injections are generally quick. Some may experience slight swelling or tenderness afterward, but this usually subsides within a few hours.

How many sessions do I need?

The number of sessions required varies based on individual goals and skin condition. Typically, a series of 3 to 4 initial treatments spaced a few weeks apart is recommended for optimal results, followed by maintenance sessions as needed.

Polynucleotide Prices

Polynucleotide treatments vary in price depending on factors such as formulation, concentration, and regenerative potential. These treatments work by stimulating cellular repair, improving skin quality, and enhancing collagen production. More advanced formulations or higher concentrations may come at a higher price, but all polynucleotide treatments provide long-term skin benefits.

As the market continues to evolve with new and improved products, it is advisable to consult your practitioner to determine the best option for your skin concerns, goals, and budget.

Lumi Eyes Pro

1x £120

3x £260

Illuma Luna

1x £130

3x £300

Pure Hilo (Skin Booster with Polynucleotides)

1x £180

3x £450

Vitaran I (1ml syringe for smaller areas)

1x £160

3x £350

Vitaran II (2ml syringe for larger areas)

1x £200

3x £430

*prices and products subject to change

THE PROCEDURE

Pre-Procedure Preparation: Before the polynucleotide treatment, it's advisable to have a consultation with your practitioner to discuss your specific skin concerns, desired outcomes, and medical history. During this consultation, any contraindications will be assessed, and a tailored treatment plan will be created.

Skin Cleansing and Numbing: On the day of the procedure, the practitioner will begin by thoroughly cleansing the treatment area to remove any makeup, dirt, or oils. Depending on the individual’s sensitivity, a topical numbing cream may be applied to minimise discomfort during the injections. This typically takes about 20-30 minutes to take effect.

Injection of Polynucleotides: Using a fine needle or cannula, the practitioner will inject the polynucleotide solution into the superficial to mid-dermal layers of the skin. These injections are strategically placed to stimulate regeneration, enhance hydration, and improve skin elasticity. Polynucleotides typically create more prominent bumps at the injection sites, which is a normal response as the product integrates and begins working within the tissue. The depth and technique of injection may vary depending on the product used and the treatment goals.

Duration of the Procedure: The procedure typically lasts 30 to 60 minutes, depending on the areas treated and the client’s specific needs. Most individuals experience mild discomfort, often described as a slight pinch or sting, but this is generally well tolerated.

Post-Procedure Care: After treatment, visible bumps at the injection sites are expected and usually subside within 24 to 72 hours as the product is absorbed. Mild redness, swelling, or tenderness is also common but temporary. Your practitioner will provide aftercare instructions, which may include avoiding facials, strenuous exercise, sun exposure, and active skincare ingredients for the first 24 to 48 hours to support optimal healing.

Follow-Up Treatments: For best results, a course of polynucleotide treatments is usually recommended, with sessions spaced 2 to 4 weeks apart depending on the treatment plan. Maintenance sessions may be suggested every few months to sustain long-term skin regeneration and collagen stimulation.

By understanding the process and following post-treatment care, clients can achieve long-lasting improvements in skin quality, resilience, and overall radiance with polynucleotide therapy.

BOOK NOW

Polynucleotides

WHAT IS IT?

​​